Inhaled amyl nitrites (or poppers) are a recreational drug used during parties and sexual activities. They induce muscle relaxation, euphoria and heightened sexual sensation [1]. Direct skin contact causes irritant dermatitis, which is usually located on the face and regresses without scarring [1]. However, contact dermatitis may occur in unusual areas in the case of leakage of the vial [2]. We report an unusual case of contact dermatitis localized on the breast of a young adult.